Company Filing History:
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1 out of 247 Years Active: 2001
Title: Claes Juhlin: Innovator in Calcium Sensor Protein Research
Introduction
Claes Juhlin is a notable inventor based in Uppsala, Sweden. He has made significant contributions to the field of biochemistry, particularly in the study of calcium sensor proteins. With a total of 2 patents, his work has implications for understanding calcium regulation in various organ systems.
Latest Patents
Juhlin's latest patents focus on the isolation of nucleic acids encoding human calcium sensor proteins. One of his inventions relates to a cDNA clone that encodes the calcium sensor found in human placenta. Subsequent Northern blots have confirmed mRNA expression in human parathyroid and kidney tubule cells. His research demonstrates close sequence similarity with the rat Heymann nephritis antigen, a glycoprotein known for its calcium binding ability. Immunohistochemistry has substantiated a tissue distribution of the calcium sensor protein similar to that previously described for the Heymann antigen. Juhlin proposes that this calcium sensor protein serves as a universal sensor for recognizing variations in extracellular calcium, playing a crucial role in calcium regulation across different organ systems. The protein belongs to the LDL-superfamily of glycoproteins, which are primarily known to function as protein receptors while also possessing important calcium binding capabilities.
Career Highlights
Throughout his career, Claes Juhlin has worked with prominent companies in the pharmaceutical industry, including Rhone-Poulenc Rorer Pharmaceuticals Inc. and Rhone-Poulenc Rorer S.A. His experience in these organizations has contributed to his expertise in the field of biochemistry and patent development.
Collaborations
Juhlin has collaborated with notable colleagues such as Göran Akerström and Lars Rask. Their combined efforts have furthered research in the area of calcium sensor proteins and their applications.
Conclusion
Claes Juhlin's innovative work in the field of calcium sensor proteins highlights his significant contributions to biochemistry and patent development. His research continues to influence the understanding of calcium regulation in human physiology.