Location History:
- Monmouth Junction, NJ (US) (1991)
- Cockeysville, MD (US) (1991)
Company Filing History:
Years Active: 1991
Title: Ciro J Spagnuolo: Innovator in Anticholinergic Compounds
Introduction
Ciro J Spagnuolo is a notable inventor based in Monmouth Junction, NJ (US). He has made significant contributions to the field of medicinal chemistry, particularly in the development of compounds with anticholinergic activity. With a total of two patents to his name, Spagnuolo's work has implications for treating various medical conditions.
Latest Patents
Spagnuolo's latest patents include innovative furanone compounds and compositions that exhibit anticholinergic activity. One of his notable inventions is the 5-(1-(imidazol)methyl)-3,3-disubstituted-2(3H)furanone derivatives. These compounds are characterized by a specific formula that includes a 4,5-unsaturated or 4,5-dihydrofuranone ring. Additionally, he has developed 1-Phenyl-7-substituted-hept-5-yn-2-ones, which are substituted with various groups at the 1-position and an amino or related group at the 7-position. These compounds are particularly effective as M1-AChR antagonists and are useful in treating neurogenic bladder disorders.
Career Highlights
Ciro J Spagnuolo is associated with Marion Merrell Dow Inc., where he has been instrumental in advancing research in pharmacology. His work has led to the development of compounds that are not only innovative but also have practical applications in medicine. His contributions have been recognized within the industry, showcasing his expertise and dedication to improving healthcare solutions.
Collaborations
Throughout his career, Spagnuolo has collaborated with notable colleagues, including Carl Kaiser and Theodore C Adams. These partnerships have fostered a collaborative environment that enhances the research and development of new medicinal compounds.
Conclusion
Ciro J Spagnuolo's contributions to the field of medicinal chemistry, particularly in the area of anticholinergic compounds, highlight his innovative spirit and commitment to advancing healthcare. His patents reflect a deep understanding of pharmacology and a dedication to improving treatment options for patients.