Cira Rinaudo

Title: Cira Rinaudo: Innovator in Gene Therapy

Introduction

Cira Rinaudo is a prominent inventor based in Palermo, Italy. She has made significant contributions to the field of gene therapy, particularly through her innovative work on DNA molecules that encode hormone-dependent forms of adeno-associated virus rep proteins. Her research has the potential to advance therapeutic applications in genetic medicine.

Latest Patents

Cira Rinaudo holds a patent for "DNA molecules encoding hormone-dependent forms of the adeno-associated virus rep proteins." This invention focuses on the hormone-dependent forms of Rep 78 and Rep 68 proteins of the Adeno-associated virus (AAV). These proteins are obtained by fusing specific mutants with the hormone binding domain (HBD) of steroid hormone receptors. The patent also describes a method for the hormonal regulation of the activity of the fusion products Rep78/68-HBD, which can be inserted into eukaryotic cells using viral or non-viral systems. This method aims to direct the stable integration of DNA sequences into specific regions of the host human genome for therapeutic purposes.

Career Highlights

Cira Rinaudo is affiliated with the Instituto di Ricerche di Biologia Molecolare P. Angeletti S.p.a., where she continues her groundbreaking research. Her work has garnered attention for its innovative approach to gene therapy and its implications for treating genetic disorders.

Collaborations

Cira has collaborated with notable scientists in her field, including Carlo Toniatti and Gennaro Ciliberto. These collaborations have further enriched her research and contributed to advancements in gene therapy.

Conclusion

Cira Rinaudo's contributions to the field of gene therapy through her innovative patents and collaborations highlight her role as a leading inventor. Her work has the potential to significantly impact therapeutic strategies in genetic medicine.