Company Filing History:
Years Active: 2023-2025
Title: Innovations by Inventor Cindy C T Wan
Introduction
Cindy C T Wan is a notable inventor based in San Francisco, CA. He has made significant contributions to the field of biotechnology, particularly in enhancing reverse transcriptase activity. With a total of 2 patents, his work has implications for various applications in molecular biology.
Latest Patents
Cindy's latest patents focus on compositions and methods for enhancing reverse transcriptase (RT) activity and reducing the inhibition of RT by various inhibitors, such as formalin, tannic acid, and heparin. The subject application details how RT inhibition can be mitigated by adding potassium glutamate, histidine hydrochloride monohydrate, poloxamer 188, or combinations thereof to a reaction mixture containing a polymerase. Additionally, RT activity can be enhanced through the incorporation of polyvinyl sulfonic acid sodium salt (PVSA) into the reaction mixture. The patents also provide oligonucleotide primers designed for reverse transcription of target sequences, which can have either high or low GC content. Methods for utilizing RT inhibition reducers or enhancers in compositions with RNA templates are also outlined, improving RT yield, sensitivity, and tolerance to various chemicals.
Career Highlights
Cindy C T Wan is currently employed at Bio-Rad Laboratories, Inc., where he continues to innovate in the field of biotechnology. His work is instrumental in advancing techniques that enhance the efficiency of reverse transcription processes.
Collaborations
Cindy has collaborated with notable colleagues, including Xiangdong Meng and Xiaosong Gong, contributing to a dynamic research environment that fosters innovation and development in their field.
Conclusion
Cindy C T Wan's contributions to biotechnology through his patents and work at Bio-Rad Laboratories, Inc. highlight his role as a significant inventor in enhancing reverse transcriptase activity. His innovative approaches are paving the way for advancements in molecular biology applications.