Company Filing History:
Years Active: 1994-1995
Title: Innovations of Chunshi Li in Stereoselective Preparation
Introduction
Chunshi Li is a notable inventor based in Hoboken, NJ (US). He has made significant contributions to the field of chemistry, particularly in the stereoselective preparation of amino acids. With a total of 2 patents, his work has implications for various applications in pharmaceuticals and biochemistry.
Latest Patents
Chunshi Li's latest patents include a process for the stereoselective preparation of L-alanyl-L-proline. This innovative method involves the catalytic hydrogenation of N-(2-iminopropionyl)-L-proline in the presence of a metal hydrogenolysis catalyst at a pH of less than about 4. Additionally, he has disclosed improved processes for the production of N-pyruvyl-L-proline, where L-proline reacts with a 2,2-disubstituted propionyl halide at a pH of at least 9. This reaction produces an L-proline intermediate, which is then hydrolyzed at a pH range of about 6.5 to about 8.5 to yield N-pyruvyl-L-proline.
Career Highlights
Chunshi Li is currently associated with Celgene Corporation, where he continues to advance his research and innovations. His work has been instrumental in developing new methodologies that enhance the efficiency and effectiveness of chemical processes.
Collaborations
Chunshi Li has collaborated with esteemed colleagues such as Beverly W Burbaum and George W Matcham. These partnerships have fostered a collaborative environment that encourages innovation and the sharing of ideas.
Conclusion
Chunshi Li's contributions to the field of chemistry, particularly in the stereoselective preparation of amino acids, highlight his role as a significant inventor. His patents and collaborations reflect a commitment to advancing scientific knowledge and practical applications in the industry.