Chrystelle Aillaud

Title: Innovations of Chrystelle Aillaud in Pharmaceutical Research

Introduction

Chrystelle Aillaud is a notable inventor based in Romans sur Isère, France. She has made significant contributions to the field of pharmaceutical research, particularly in the treatment of diseases associated with tubulin carboxypeptidases. Her innovative work has led to the development of methods and compositions that hold promise for addressing various neurological and cardiovascular disorders.

Latest Patents

Chrystelle Aillaud holds a patent for "Methods and pharmaceutical compositions for treating tubulin carboxypeptidases associated diseases." This patent describes the use of chemical proteomics with a potent unique irreversible inhibitor. The research identifies the major brain tubulin carboxypeptidase (TCP) as a complex of vasohibin-1 (VASH1) with the Small Vasohibin-Binding Protein (SVBP). The findings reveal that VASH1 and its homologue, vasohibin-2 (VASH2), exhibit robust and specific Tyr/Phe carboxypeptidase activity on microtubules when complexed with SVBP. The invention establishes vasohibin/SVBP complexes as TCP enzymes, providing a foundation for developing treatments for associated diseases.

Career Highlights

Throughout her career, Chrystelle Aillaud has worked with esteemed organizations, including Les Laboratoires Servier and the Institut National de la Santé et de la Recherche Médicale. Her research has significantly advanced the understanding of tubulin carboxypeptidases and their role in various diseases.

Collaborations

Chrystelle has collaborated with notable colleagues, including Annie Andrieux and Marie-José Moutin. These partnerships have contributed to her innovative research and the successful development of her patent.

Conclusion

Chrystelle Aillaud's contributions to pharmaceutical research exemplify the impact of innovation in addressing complex medical challenges. Her work continues to pave the way for new treatments for neurological and cardiovascular diseases.