Company Filing History:
Years Active: 1996
Title: Christopher M Ott: Innovator in Oligonucleotide Sequencing
Introduction
Christopher M Ott is a notable inventor based in Oakham, MA (US). He has made significant contributions to the field of biotechnology, particularly in the area of oligonucleotide sequencing. His innovative methods have the potential to advance genetic research and diagnostics.
Latest Patents
Christopher M Ott holds a patent for a method of sequencing oligonucleotides. The patent, titled "Method of sequencing oligonucleotides," discloses a technique for determining the nucleotide sequence of a target oligonucleotide. This method involves preparing a single-stranded ligation product that contains both the target oligonucleotide and an auxiliary oligonucleotide. A primer, which is complementary to a portion of the auxiliary oligonucleotide and has a label covalently attached, is annealed to the ligation product. The primer is then extended using chain-extending and chain-terminating nucleoside triphosphates in the presence of a polymerase, resulting in multiple primer extension products. These products are separated based on their base length, allowing for the determination of the nucleoside sequence of the target oligonucleotide.
Career Highlights
Christopher M Ott is associated with Hybridon, Inc., where he has been instrumental in developing innovative sequencing methods. His work has contributed to advancements in the biotechnology sector, particularly in genetic analysis and research.
Collaborations
Throughout his career, Christopher has collaborated with notable colleagues, including Aharon S Cohen and Alexei Belenky. These collaborations have fostered a productive environment for innovation and research in the field of biotechnology.
Conclusion
Christopher M Ott is a distinguished inventor whose work in oligonucleotide sequencing has the potential to impact genetic research significantly. His contributions to Hybridon, Inc. and collaborations with other experts highlight his commitment to advancing biotechnology.