Location History:
- Sunnyvale, CA (US) (2012 - 2014)
- Redwood City, CA (US) (2014)
- Santa Clara, CO (US) (2019)
- Santa Clara, CA (US) (2014 - 2022)
Company Filing History:
Years Active: 2012-2025
Title: Christopher K. Savile: Innovator in Biocatalysis and Chiral Compound Synthesis
Introduction: Christopher K. Savile is a prominent inventor based in Santa Clara, Colorado, known for his significant contributions to the field of biocatalysis. With an impressive portfolio of 31 patents, Savile has been at the forefront of developing engineered enzymes that possess improved properties for various applications in biotechnology.
Latest Patents: Among his latest achievements, Savile has worked on engineered ketoreductase polypeptides. These innovations focus on enhancing the properties of ketoreductase enzymes compared to their naturally occurring wild-type counterparts. His work includes polynucleotides that encode these engineered enzymes, alongside host cells capable of expressing them. A notable application of this technology is in synthesizing chiral compounds, such as converting N-methyl-3-keto-3-(2-thienyl)-1-propanamine to (S)-N-methyl-3-hydroxy-3-(2-thienyl)-1-propanamine. Additionally, he has explored transaminase reactions, contributing to methods that utilize transaminase polypeptides for synthesizing chiral amines from prochiral ketones.
Career Highlights: Christopher K. Savile has made a significant impact in the biotechnology sector through his role at Codexis, Inc. His innovations have been pivotal in advancing biocatalysis, making him a key figure in the development of efficient and sustainable chemical processes.
Collaborations: During his career, Savile has collaborated with renowned colleagues such as Emily Mundorff and Gjalt W. Huisman. These partnerships have resulted in groundbreaking advancements within the field, further highlighting the collaborative spirit that drives innovation in scientific research.
Conclusion: Christopher K. Savile continues to be a leading inventor in the biocatalysis domain. His extensive patent portfolio underscores his commitment to enhancing enzyme technology for effective chiral synthesis, evidencing the importance of his contributions to the field and the broader implications for biotechnology advancements.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.