Christopher John Gregg

Title: Christopher John Gregg: Innovator in Biochemical Engineering

Introduction

Christopher John Gregg is a notable inventor based in Roslindale, MA (US). He has made significant contributions to the field of biochemical engineering, particularly in the development of novel polypeptides and their applications. With a total of 6 patents, Gregg's work has the potential to impact various industries, including biotechnology and pharmaceuticals.

Latest Patents

One of Gregg's latest patents is titled "Non-standard amino acid containing compositions and uses thereof." This invention provides a stabilized DNase I polypeptide that contains a non-standard amino acid, which maintains its enzymatic activity even under harsh conditions, such as reducing environments. The stabilized DNase I polypeptide exhibits higher enzymatic activity in these conditions compared to a corresponding DNase I polypeptide without the non-standard amino acids. Additionally, the patent includes polynucleotides encoding the stabilized DNase I polypeptide, cells for expressing and/or producing the polypeptide, and methods for its use.

Another significant patent by Gregg is "Production of seleno-biologics in genomically recoded organisms." This invention focuses on polypeptides that are stabilized by diselenide bonds between selenocysteine amino acids. The methods developed for producing these polypeptides in genomically recoded organisms (GRO) can be scaled up for industrial production. Diselenides can be substituted into polypeptides without disrupting their three-dimensional structure, rendering them resistant to reduction when exposed to blood serum or reducing components within cells.

Career Highlights

Gregg has worked with prestigious institutions, including Harvard College and Gro Biosciences Inc. His experience in these organizations has allowed him to refine his expertise in biochemical research and innovation.

Collaborations

Throughout his career, Gregg has collaborated with notable figures in the field, including Marc J. Lajoie and George M. Church. These collaborations have further enhanced his research and development efforts.

Conclusion

Christopher John Gregg is a prominent inventor whose work in biochemical engineering has led to significant advancements in the field. His innovative patents and collaborations reflect his commitment to pushing the boundaries of scientific research and application.