Pittsburgh, PA, United States of America

Christopher H Evans



Average Co-Inventor Count = 3.1

ph-index = 7

Forward Citations = 146(Granted Patents)


Location History:

  • Pittsburgh, PA (US) (1998 - 2006)
  • Cohasset, MA (US) (2006)

Company Filing History:


Years Active: 1998-2006

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8 patents (USPTO):Explore Patents

Title: Christopher H Evans: Innovator in Gene Delivery and Bone Pathology Treatment

Introduction

Christopher H Evans is a prominent inventor based in Pittsburgh, PA (US), known for his significant contributions to the field of gene delivery and treatment of bone pathologies. With a total of 8 patents, Evans has made remarkable strides in developing innovative methods for delivering therapeutic agents to target cells.

Latest Patents

One of Evans' latest patents is titled "Viral and non-viral vectors as vehicles for delivering transgenes for treating bone pathologies." This invention relates to a method for treating bone pathologies by delivering a viral or non-viral delivery vehicle that contains genetic information encoding a therapeutic osteoinductive factor. The method enables target cells to produce the osteoinductive factor at the site of the bone pathology without the need for cumbersome ex vivo techniques or additional matrix or scaffolding agents. The delivery vehicles include a variety of options such as adenoviruses, adeno-associated viruses, retroviruses, herpes simplex viruses, liposomes, and plasmids. The osteoinductive factors can include growth factors, cytokines, and their inhibitors.

Another significant patent by Evans is "Gene transfer for studying and treating a connective tissue of a mammalian host." This patent discloses methods for introducing genes encoding products into target cells of a mammalian host for therapeutic purposes. The methods utilize recombinant techniques to produce vector molecules containing the desired genes, which are then used to infect the target cells. This patent also includes a method for producing an animal model to study connective tissue pathology.

Career Highlights

Evans is affiliated with the University of Pittsburgh, where he continues to advance research in gene therapy and regenerative medicine. His work has been instrumental in developing new approaches to treat various bone and connective tissue disorders.

Collaborations

Some of Evans' notable collaborators include Paul David Robbins and Joseph C Glorioso, who have contributed to his research endeavors and innovations in the field.

Conclusion

Christopher H Evans stands out as a leading inventor in the realm of gene delivery and treatment of bone pathologies. His innovative patents and ongoing research at the University of Pittsburgh continue to pave the way for advancements in medical therapies.

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