Christine Ko

Title: **Innovative Journey of Christine Ko in Biotechnology**

Introduction

Christine Ko, an accomplished inventor based in Boulder, CO, has made significant contributions to the field of biotechnology. With a total of three patents to her name, she has focused on the development and enhancement of biological proteins that have great potential for therapeutic applications.

Latest Patents

Christine's latest patents highlight her groundbreaking work in neurotrophic factors and immunology. One of her notable inventions is related to a purified ciliary neurotrophic factor (CNTF), specifically a sciatic nerve CNTF (SN-CNTF). This invention boasts a significant increase in specific activity—greater than 25,000-fold compared to crude extracts. The patent also provides detailed amino acid data for SN-CNTF, along with innovative methods for its application in screening cDNA and genomic libraries. Furthermore, Christine has described recombinant-DNA techniques for producing biologically active CNTF.

Another important patent focuses on DNA encoding an 85kd polypeptide that is instrumental in diagnosing Mycoplasma infections in animals. These polypeptides are capable of eliciting immune responses in swine that previously had no exposure to Mycoplasma. The patent outlines recombinant DNA methods for production and details vaccination composition strategies to enhance animal health.

Career Highlights

Throughout her career, Christine Ko has worked with prominent companies in the biotechnology sector, including Synergen, Inc. and Amgen Inc. Her experiences in these organizations have undoubtedly shaped her innovative spirit and technical expertise.

Collaborations

Christine's journey has also been marked by collaborations with esteemed colleagues in the field. Notable coworkers include Franklin D Collins and Leu-Fen H Lin, who have contributed to her research and development initiatives. Such collaborations are essential in fostering innovation and advancing scientific discoveries.

Conclusion

Christine Ko's dedication to her field and her impressive portfolio of patents demonstrate her significant impact on biotechnology. Her contributions not only enhance our understanding of biological proteins but also pave the way for future advancements in medical diagnostics and therapeutics. With continued collaboration and innovation, the future holds great promise for her ongoing research efforts.