Company Filing History:
2 out of 18 
2 out of 6 Years Active: 2010-2013
Title: Christina Bottino: Innovator in Therapeutic and Diagnostic Methods
Introduction
Christina Bottino is a prominent inventor based in Genoa, Italy. She has made significant contributions to the field of therapeutic and diagnostic methods, particularly in relation to cancer treatment and immune response modulation. With a total of 2 patents, her work focuses on innovative approaches to enhance NK cell cytotoxicity and improve disease diagnosis.
Latest Patents
One of Christina Bottino's latest patents involves therapeutic and diagnostic methods and compositions targeting the 4Ig-B7-H3 protein and its counterpart NK cell receptor. This invention identifies the 4Ig-B7-H3 protein as a tumor-associated molecule that protects against NK cell-mediated lysis. The patent provides compounds that interfere with the interactions between the 4Ig-B7-H3 protein and its receptor, which can be utilized to enhance NK cell cytotoxicity. Additionally, the compounds are designed to bind to 4Ig-B7-H3-expressing cells to inhibit or eliminate them. These compounds are particularly beneficial in treating tumors, inflammatory conditions, infections, and transplantation. The invention also includes methods for diagnosing diseases by detecting the presence of the 4Ig-B7-H3 protein.
Career Highlights
Throughout her career, Christina Bottino has worked with notable organizations, including Innate Pharma and the University of Genova. Her research has significantly advanced the understanding of immune responses and therapeutic interventions in oncology.
Collaborations
Christina has collaborated with esteemed colleagues such as Alessandro Moretta and Roberta Castriconi, contributing to a rich exchange of ideas and innovations in her field.
Conclusion
Christina Bottino's work exemplifies the impact of innovative research in therapeutic and diagnostic methods. Her contributions continue to pave the way for advancements in cancer treatment and immune system modulation.