This inventor holds 4 USPTO granted patents and 1 published patent application and 1 EPO patent. Top assignee: Epigenomics Ag. Active years: 2007-2017.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
Years Active: 2007-2017
Title: Christian Piepenbrock: Innovator in Genomic DNA Methylation Detection
Introduction
Christian Piepenbrock is a notable inventor based in Berlin, Germany. He has made significant contributions to the field of genomic research, particularly in the area of DNA methylation. With a total of 4 patents, his work has advanced the understanding of genetic modifications and their implications.
Latest Patents
One of his latest patents is a method for determining the degree of methylation of defined cytosines in genomic DNA in the sequence context of 5'-CpG-3′. This method involves chemically treating genomic DNA to convert cytosine bases to uracil while leaving 5-methylcytosine bases unchanged. The segments containing the specific cytosine are then amplified and labeled for detection, allowing for the assessment of methylation levels based on hybridization ratios.
Another significant patent focuses on the quantitative determination of the degree of methylation of cytosines in CpG positions. This invention describes a method for sequencing nucleic acids treated with bisulfite, enabling the validation of sequence information. It outlines how to standardize signal intensity data and determine a correction factor for improved estimation of methylation levels.
Career Highlights
Christian Piepenbrock is currently associated with Epigenomics AG, a company dedicated to developing innovative diagnostic solutions in the field of epigenetics. His expertise in genomic research has positioned him as a key figure in advancing methodologies for DNA analysis.
Collaborations
Throughout his career, Piepenbrock has collaborated with notable colleagues, including Kurt Berlin and Alexander Olek. These partnerships have fostered a collaborative environment that enhances research and innovation in the field of epigenetics.
Conclusion
Christian Piepenbrock's contributions to the field of genomic DNA methylation detection are invaluable. His innovative methods and patents continue to influence research and diagnostics in epigenetics.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile