Frankfurt am Main, Germany

Christian Engel


 

Average Co-Inventor Count = 6.8

ph-index = 3

Forward Citations = 14(Granted Patents)


Company Filing History:


Years Active: 2007-2016

where 'Filed Patents' based on already Granted Patents

12 patents (USPTO):

Title: Christian Engel: Innovator in Antibody Research

Introduction

Christian Engel is a prominent inventor based in Frankfurt am Main, Germany. He has made significant contributions to the field of biotechnology, particularly in the development of novel antibodies and therapeutic agents. With a total of 12 patents to his name, Engel's work has the potential to impact the treatment of various vascular diseases.

Latest Patents

One of Engel's latest patents is focused on antagonist antibodies and their Fab fragments against Glycoprotein VI (GPVI). This invention discloses novel antibodies that specifically bind to the human platelet membrane protein GPVI and their monovalent fragments or derivatives. These antibodies are derived from hybridoma clone 390 and are capable of inducing a GPVI depletion phenotype. The antibodies and Fab fragments can block collagen binding, thereby preventing platelet activation by collagen. Engel's invention also includes hybridoma clones and expression plasmids for the production of these antibodies and Fab fragments. Furthermore, it refers to the uses of monovalent antibody fragments in manufacturing research, diagnostic, and immunotherapeutic agents for treating thrombosis and other vascular diseases. Another significant patent involves oxathiazine derivatives substituted with carbocycles or heterocycles, which are suitable for treating hyperglycemia.

Career Highlights

Throughout his career, Christian Engel has worked with notable companies, including Sanofi and Sanofi-Aventis Deutschland GmbH. His experience in these organizations has contributed to his expertise in the field of antibody research and development.

Collaborations

Engel has collaborated with several professionals in his field, including Thomas Boehme and Stefan Guessregen. These collaborations have likely enhanced his research and innovation capabilities.

Conclusion

Christian Engel is a distinguished inventor whose work in antibody research has led to significant advancements in medical treatments. His patents reflect a commitment to improving healthcare through innovative solutions.

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