Christian C Simonsen, Sr

Title: The Innovations of Christian C Simonsen, Sr.

Introduction

Christian C Simonsen, Sr. is a notable inventor based in San Jose, CA. He has made significant contributions to the field of biotechnology, particularly in the development of protease inhibitors and expression vectors. With a total of 2 patents, his work has had a substantial impact on diagnostic and therapeutic applications.

Latest Patents

One of his latest patents is focused on recombinant purified protease nexin. This patent involves DNA segments encoding two slightly different forms of protease nexin I, specifically PN-I.alpha. and PN-I.beta. These segments are cloned and expressed to provide practical quantities of PN-I for diagnostic and therapeutic use. PN-I serves as a serine protease inhibitor, which is useful in controlling conditions mediated by proteolytic activity. Another significant patent is related to polycistronic expression vector construction. This patent describes a polycistronic construction of xenogeneic sequences that can be expressed in eukaryotic cells. The construction allows for the amplification of DHFR encoding sequences under the control of the same promoter, facilitating the coamplification of foreign genes.

Career Highlights

Throughout his career, Christian has worked with prominent companies in the biotechnology sector, including Genentech, Inc. and Incyte Pharmaceuticals, Inc. His experience in these organizations has contributed to his expertise and innovative capabilities in the field.

Collaborations

Christian has collaborated with notable individuals in the industry, including Arthur D Levinson and Michael P McGrogan. These collaborations have further enhanced his work and contributions to biotechnology.

Conclusion

Christian C Simonsen, Sr. is a distinguished inventor whose work in biotechnology has led to important advancements in protease inhibitors and expression vectors. His patents reflect his commitment to innovation and the betterment of therapeutic applications.