Christian Brand

Title: Christian Brand: Innovator in Radioligand Imaging

Introduction

Christian Brand is a notable inventor based in New York, NY (US). He has made significant contributions to the field of medical imaging, particularly in the development of radioligands for pretargeted PET imaging. His innovative work aims to enhance cancer detection and treatment methodologies.

Latest Patents

Christian Brand holds a patent for "Radioligands for pretargeted PET imaging and methods of their therapeutic use." This patent describes Tz/TCO-based pretargeting strategies utilizing an Al[F]-NOTA-labeled tetrazine radioligand. This imaging strategy allows for the delineation of cancer at earlier time points compared to other imaging techniques. Additionally, it reduces the radiation dose to healthy tissues when compared to directly labeled antibodies. The achievement of Al-based F imaging of small molecules, such as tetrazine, is groundbreaking, as it had not been previously accomplished due to the decomposition of tetrazine during radiofluorination. The advantages of radiofluorination over other radiolabeling methods include a shorter half-life and greater availability for integration into hospital workflows.

Career Highlights

Christian Brand is affiliated with the Memorial Sloan Kettering Cancer Center, where he continues to advance his research and innovations in medical imaging. His work is pivotal in improving cancer diagnosis and treatment options.

Collaborations

Some of his notable coworkers include Brian Zeglis and Jason S Lewis, who contribute to the collaborative efforts in his research endeavors.

Conclusion

Christian Brand's contributions to the field of radioligand imaging represent a significant advancement in cancer detection and treatment. His innovative approaches are paving the way for improved medical imaging techniques that can benefit patients worldwide.