Christer Jan Mattsson

Title: Innovations of Christer Jan Mattsson

Introduction

Christer Jan Mattsson is a notable inventor based in Sundbyberg, Sweden. He has made significant contributions to the field of medicinal chemistry, particularly in the development of heparin derivatives. With a total of 2 patents, his work has implications for the treatment of various vascular disorders.

Latest Patents

Mattsson's latest patents include innovative heparin derivatives and processes for their preparation. One of his key inventions relates to new heparin derivatives derived from bovine or porcine heparin. These derivatives possess a molecular weight equal to or larger than standard heparin and exhibit a sulfur content that is equal to or higher than that of the starting heparin, or at least 13% w/w. They demonstrate anticoagulant activity in the anti-FXa assay of less than 10% of the standard heparin from which they were derived. Additionally, these derivatives show a ratio of APTT activity over anti-FXa activity of 3-35 and a reduced prolongation of bleeding time compared to the standard heparin. Furthermore, they enhance the rate of development of coronary collaterals in dogs, equal to or better than clinically used heparin. The invention also outlines processes for the preparation of these new heparin derivatives, which can be utilized in the manufacturing of medicaments for treating ischemic heart disease and related vascular disorders.

Career Highlights

Throughout his career, Mattsson has worked with prominent companies such as Pharmacia & Upjohn Aktiebolag and Pharmacia AB. His experience in these organizations has contributed to his expertise in the field of pharmaceutical innovations.

Collaborations

Mattsson has collaborated with notable individuals in his field, including Michael Per Weber and Carl Magnus Erik Svahn. These collaborations have likely enriched his research and development efforts.

Conclusion

Christer Jan Mattsson's contributions to the field of medicinal chemistry, particularly through his innovative heparin derivatives, highlight his role as a significant inventor. His work continues to have a positive impact on the treatment of vascular disorders.