Company Filing History:
Years Active: 2016
Title: Chris Szent-Gyorgyi: Innovator in Fluorescence Detection
Introduction
Chris Szent-Gyorgyi is an accomplished inventor based in Pittsburgh, PA. He has made significant contributions to the field of fluorescence detection through his innovative work. His research focuses on enhancing the effectiveness of imaging systems using advanced molecular designs.
Latest Patents
Szent-Gyorgyi holds a patent for "Quenched dendrimeric dyes for fluorescence detection." This invention presents designs for high extinction quenched 'dyedrons' that can be activated by converting a single acceptor/quencher in the molecular assembly to a fluorescent state. The quencher is activated by noncovalent binding to a unique complementary expressible fluorogen activating peptide (FAP). This mechanism allows the quencher to act as a homogeneous switch, efficiently receiving energy from each donor molecule of the dendronic antenna and releasing it as fluorescence only when activated by binding. The cumulative effect of the multiple dyes on the antenna results in dramatic enhancements in the effective brightness of the probe in standard imaging systems. This approach provides a set of probes with exceptional brightness, specifically targeted to an expressed tag that activates the fluorescence of the dyedron.
Career Highlights
Chris Szent-Gyorgyi is affiliated with Carnegie Mellon University, where he continues to advance his research and contribute to the scientific community. His work has garnered attention for its potential applications in various fields, including biomedical imaging and diagnostics.
Collaborations
Some of his notable coworkers include Marcel Pierre Bruchez and Lauren A Ernst. Their collaborative efforts have further enriched the research environment and fostered innovation in fluorescence detection technologies.
Conclusion
Chris Szent-Gyorgyi's contributions to the field of fluorescence detection exemplify the impact of innovative thinking in scientific research. His patented designs and ongoing work at Carnegie Mellon University continue to push the boundaries of what is possible in imaging technologies.