Chris Nehme

Title: Chris Nehme: Innovator in Spatial Multiomics Technology

Introduction

Chris Nehme is a prominent inventor based in Bergisch Gladbach, Germany. He has made significant contributions to the field of spatial multiomics, particularly through his innovative patent that enhances our understanding of tissue heterogeneity.

Latest Patents

Chris Nehme holds a patent for a method and instrumentation for spatial multiomics using SUMI-technology. This groundbreaking technology allows for the microscopy imaging of multiple mRNAs, proteins, and metabolites to be spatially resolved at a subcellular level. The invention, known as SUMI-Seq, combines the use of Spatial Unique Molecular Identifier in situ sequencing with in vitro sequencing of rolonies derived from rolling circle amplification. This method targets portions of RNA or cDNA transcripts at a subcellular level, overcoming limitations in the amount of transcripts and the length of sequences that can be analyzed. Additionally, the SUMI-Seq method can utilize circular oligonucleotides to spatially resolve proteins and metabolites, providing comprehensive multiomics results.

Career Highlights

Chris Nehme is currently employed at Miltenyi Biotec B.V. & Co. KG, where he continues to advance his research in spatial multiomics. His work is crucial for understanding complex biological systems, particularly within the tumor microenvironment.

Collaborations

Chris collaborates with notable colleagues, including Thomas Rothmann and Robert Pinard, who contribute to his research endeavors and innovations in the field.

Conclusion

Chris Nehme's contributions to spatial multiomics through his innovative patent exemplify the importance of advancements in microscopy imaging technology. His work not only enhances our understanding of molecular information but also paves the way for future research in tissue heterogeneity.