Hamilton, Canada

Chitra Sundararajan

USPTO Granted Patents = 2 

Average Co-Inventor Count = 5.0

ph-index = 2

Forward Citations = 99(Granted Patents)


Company Filing History:


Years Active: 2010-2011

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2 patents (USPTO):Explore Patents

Title: Chitra Sundararajan: Innovator in Tricyclic-Bis-Enone Derivatives

Introduction

Chitra Sundararajan is a prominent inventor based in Hamilton, Canada. She has made significant contributions to the field of medicinal chemistry, particularly through her innovative work on tricyclic-bis-enone derivatives. With a total of 2 patents, her research focuses on developing compounds that have the potential to treat various diseases.

Latest Patents

Sundararajan's latest patents describe novel tricyclic-bis-enone derivatives (TBEs), including TBE-31, TBE-34, TBE-45, and water-soluble TBEs. These inventions detail methods for preparing these compounds and demonstrate their ability to inhibit the proliferation of human myeloma cells. Additionally, they show the capacity to inhibit the induction of iNOS in cells stimulated with interferon-γ, induce heme oxygenase-1 (HO-1), and induce CD11b expression, which is a leukemia differentiation marker. The TBEs also exhibit the ability to inhibit proliferation in leukemia cells, induce apoptosis in human lung cancer, and affect other cancerous cells. These compounds are expected to be valuable agents for the treatment and prevention of various diseases, including cancer, neurological disorders, inflammation, and conditions involving oxidative stress.

Career Highlights

Chitra Sundararajan is affiliated with Dartmouth College, where she continues her research and development in medicinal chemistry. Her work has garnered attention for its potential impact on therapeutic strategies for serious health conditions.

Collaborations

Sundararajan has collaborated with notable colleagues, including Tadashi Honda and Gordon W Gribble, contributing to the advancement of her research and the development of innovative solutions in her field.

Conclusion

Chitra Sundararajan's contributions to the field of medicinal chemistry through her innovative work on tricyclic-bis-enone derivatives highlight her role as a leading inventor. Her research holds promise for the treatment of various diseases, showcasing the importance of innovation in healthcare.

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