Chitra Kotwaliwale

Title: Chitra Kotwaliwale: Innovator in Genotyping Technologies

Introduction

Chitra Kotwaliwale is a prominent inventor based in Oakland, CA (US). She has made significant contributions to the field of biotechnology, particularly in the area of genotyping technologies. With a total of 3 patents to her name, her work has the potential to impact cancer treatment and diagnostics.

Latest Patents

One of her latest patents is titled "Method for genotyping clonotype profiles using sequence tags." This invention focuses on sequence-based profiling of populations of nucleic acids through multiplex amplification and the attachment of sequence tags to target nucleic acids. The process is followed by high-throughput sequencing of the amplification product. The invention includes successive steps of primer extension, removal of unextended primers, and the addition of new primers for amplification or further primer extensions. Notably, some embodiments of this invention are directed towards minimal residual disease (MRD) analysis for patients undergoing cancer treatment. The incorporation of sequence tags into sequence reads allows for efficient determination of clonotypes and helps detect carry-over contamination from other samples tested in the same laboratory.

Career Highlights

Chitra Kotwaliwale is currently associated with Adaptive Biotechnologies Corporation, where she continues to innovate in the field of biotechnology. Her work is instrumental in advancing the understanding and treatment of various diseases, particularly cancer.

Collaborations

She collaborates with notable colleagues such as Thomas Asbury and Kieran Hervold, contributing to a dynamic research environment that fosters innovation and discovery.

Conclusion

Chitra Kotwaliwale's contributions to biotechnology, particularly in genotyping technologies, highlight her role as a leading inventor in her field. Her innovative patents and collaborations are paving the way for advancements in cancer diagnostics and treatment.