Chih-Hung Chuang

Title: Chih-Hung Chuang: Innovator in Antibody Technology

Introduction

Chih-Hung Chuang is a notable inventor based in Kaohsiung, Taiwan. He has made significant contributions to the field of biotechnology, particularly in the development of innovative antibody technologies. His work focuses on creating solutions that enhance the efficacy of protein drugs.

Latest Patents

Chuang holds a patent for an "Antibody locker for the inactivation of protein drug." This invention discloses a hinge antibody capable of being selectively activated in target cells or tissues to treat specific conditions. The hinge antibody comprises a functional antibody, two inhibitory domains, and four cleavable linkers. The functional antibody is designed to treat conditions in an activated state and consists of two light chains and two heavy chains. Each inhibitory domain includes a hinge domain of an immunoglobulin and consists of two peptide arms. The cleavable linkers connect the peptide arms of the inhibitory domains to the light and heavy chains of the functional antibody, allowing for targeted treatment.

Career Highlights

Chih-Hung Chuang has worked with prominent institutions, including Kaohsiung Medical University and Dcb-usa LLC. His experience in these organizations has allowed him to further his research and development in antibody technology.

Collaborations

Chuang has collaborated with notable colleagues such as Tian-Lu Cheng and Hsiu-Fen Ko. These partnerships have contributed to the advancement of his research and the successful development of his patented technologies.

Conclusion

Chih-Hung Chuang is a distinguished inventor whose work in antibody technology has the potential to revolutionize the treatment of various medical conditions. His innovative approaches and collaborations continue to drive advancements in the field.