Company Filing History:
Years Active: 2014-2018
Title: Chiara Bovolenta: Innovator in Lentiviral Vector Production
Introduction
Chiara Bovolenta is a prominent inventor based in Milan, Italy. She has made significant contributions to the field of biotechnology, particularly in the production of lentiviral vectors. With a total of 4 patents, her work has the potential to advance gene therapy and related applications.
Latest Patents
One of her latest patents focuses on the stable production of lentiviral vectors. This invention provides new stable packaging cell lines and producer cell lines, along with methods to obtain them. The innovative method utilizes a baculo-AAV hybrid system for stable expression of structural and regulatory lentiviral proteins. This system comprises a baculoviral backbone containing an integration cassette flanked by AAV ITR, in combination with a plasmid encoding rep protein. It allows for stable integration of the structural and regulatory HIV-1 proteins gag/pol and rev. The system also enables the creation of a first intermediate that includes only the structural and regulatory HIV proteins gag/pol and rev, which can be used as a starting point to obtain stable packaging cell lines and producer cell lines.
Career Highlights
Chiara Bovolenta is currently employed at Molmed Spa, where she continues to innovate in the field of biotechnology. Her work has garnered attention for its potential applications in gene therapy and other medical fields.
Collaborations
Some of her notable coworkers include Anna Stornaiuolo and Paolo Rizzardi, who contribute to the collaborative environment at Molmed Spa.
Conclusion
Chiara Bovolenta's contributions to the field of lentiviral vector production highlight her innovative spirit and dedication to advancing biotechnology. Her patents and work at Molmed Spa are paving the way for future developments in gene therapy.