Chi Li

Title: Innovations in Cancer Therapeutics by Inventor Chi Li

Introduction

Chi Li is an accomplished inventor based in Prospect, KY (US). He has made significant contributions to the field of cancer therapeutics, holding 2 patents that focus on innovative methods for inhibiting tumor growth and promoting apoptosis in cancer cells.

Latest Patents

One of Chi Li's latest patents is titled "Method of inhibiting lung or breast cancer growth with engineered embryonic stem-cell derived exosomes compositions." This patent provides compositions that include exosomes generated from stem cells, which have been modified to express a granulocyte-macrophage colony stimulating factor (GM-CSF) polypeptide. The methods disclosed in this patent aim to prevent and inhibit tumor growth, metastases, and induce anti-tumor immune responses in subjects.

Another significant patent is "BAX-activating cancer therapeutics." This invention focuses on the pro-apoptotic Bcl-2 protein Bax, which initiates apoptosis in various apoptotic paradigms. The patent identifies small molecule compounds that facilitate Bax insertion into mitochondrial membranes, promoting Bax-dependent apoptosis. These compounds have the potential to serve as effective anti-cancer therapeutic agents.

Career Highlights

Chi Li is associated with the University of Louisville Research Foundation, Inc., where he continues to advance his research in cancer therapeutics. His work has the potential to significantly impact the treatment of various cancers, providing new avenues for therapeutic intervention.

Collaborations

Chi Li collaborates with notable colleagues, including John W. Eaton and Kavitha Yaddanapudi. Their combined expertise enhances the research efforts in developing innovative cancer treatments.

Conclusion

Chi Li's contributions to cancer therapeutics through his innovative patents demonstrate his commitment to advancing medical science. His work holds promise for improving treatment options for patients battling cancer.