Company Filing History:
Years Active: 2023
Title: Chengyao Li: Innovator in Biomedical Technology
Introduction
Chengyao Li is a prominent inventor based in Shihezi, China. He has made significant contributions to the field of biomedical technology, particularly in the development of nanobodies targeting SARS-CoV-2. With a total of 2 patents, his work is paving the way for advancements in medical diagnostics and therapeutics.
Latest Patents
Chengyao Li's latest patents include two innovative nanobodies related to the SARS-CoV-2 virus. The first patent, titled "Nano-antibody and its application based on SARS-CoV-2 S protein," focuses on the Spike S1+S2 ECD of SARS-CoV-2. This patent describes a method for screening nanobodies against the virus using a nanobody library. The results of the ELISA test indicate that the nanobody can specifically identify the Spike S1+S2 ECD target, demonstrating a strong binding signal. The corresponding nanobody sequence is successfully constructed into a prokaryotic expression vector, achieving a purification level greater than 90%. The purified nanobody exhibits a high affinity for the two targets.
The second patent, "Nano-antibody and its application based on SARS-CoV-2 S protein S1 subunit," also targets the SARS-CoV-2 virus. This patent focuses on the Spike RBD of SARS-CoV-2 and employs a similar screening method using a nanobody library. The ELISA test results confirm the specific identification of the Spike RBD target, with a strong binding signal. Again, the corresponding nanobody sequence is constructed into a prokaryotic expression vector, achieving a purification level greater than 90%. The purified VHH nanobody shows a higher affinity for both targets.
Career Highlights
Chengyao Li is affiliated with Shihezi University, where he conducts his research and development in biomedical technology. His work has garnered attention for its potential applications in combating viral infections, particularly in the context of the ongoing global pandemic.
Collaborations
Chengyao Li collaborates with notable colleagues, including Chuangfu Chen and Peng Wu. Their combined expertise contributes to the advancement of research in the field of nanobodies and their applications.
Conclusion
Chengyao Li's innovative work in the development