Location History:
- Burlingame, CA (US) (2017 - 2022)
- Madison, WI (US) (2018 - 2023)
Company Filing History:
3 out of 4,119 
2 out of 65 
Years Active: 2017-2023
Title: Innovations of Cheng-Hsien Wu
Introduction
Cheng-Hsien Wu is a prominent inventor based in Burlingame, CA (US). He has made significant contributions to the field of biotechnology, particularly in the area of gene assembly. With a total of 5 patents, his work has paved the way for advancements in genetic engineering and molecular biology.
Latest Patents
One of his latest patents is titled "RNA-mediated gene assembly from DNA oligonucleotides." This invention focuses on methods and materials for RNA-mediated gene assembly from oligonucleotide sequences. In this process, oligonucleotides are provided in an array format, and an RNA polymerase promoter is appended to surface-bound oligonucleotides. A plurality of RNA copies of each oligonucleotide is then produced using RNA polymerase. These RNA molecules self-assemble into a desired full-length RNA transcript through hybridization and ligation. The resulting RNA transcript can be converted into double-stranded DNA, which is useful in various applications, including protein expression. Another significant patent is for "Methods for seamless nucleic acid assembly." This invention includes methods, systems, and compositions for seamless nucleic acid assembly, which encompasses in vitro recombination cloning, single-stranded hierarchical DNA assembly, and overlap extension PCR without primer removal.
Career Highlights
Cheng-Hsien Wu has worked with notable organizations such as the Wisconsin Alumni Research Foundation and Twist Bioscience Corporation. His experience in these institutions has contributed to his expertise in the field of genetic research and innovation.
Collaborations
Throughout his career, Cheng-Hsien Wu has collaborated with esteemed colleagues, including Lloyd M. Smith and Sebastian Treusch. These collaborations have further enhanced his research and development efforts in biotechnology.
Conclusion
Cheng-Hsien Wu's innovative work in RNA-mediated gene assembly and seamless nucleic acid assembly has significantly impacted the field of biotechnology. His contributions continue to influence advancements in genetic engineering and molecular biology.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.