Chen-Ming Fan

Title: The Innovations of Chen-Ming Fan

Introduction

Chen-Ming Fan is a prominent inventor based in San Francisco, MA (US). He has made significant contributions to the field of transcriptional regulation, particularly in the context of immunoglobulin genes. With a total of 3 patents, his work has had a profound impact on genetic research and biotechnology.

Latest Patents

Fan's latest patents focus on nuclear factors associated with transcriptional regulation. He describes constitutive and tissue-specific protein factors that bind to transcriptional regulatory elements of immunoglobulin genes, including both promoters and enhancers. These factors were identified and isolated through an improved assay for protein-DNA binding. His research highlights the potential to isolate genes encoding factors that positively regulate transcription, which can be employed to enhance the transcription of immunoglobulin genes. Notably, his work includes the gene encoding NF-kB, IkB, and their respective uses.

Career Highlights

Throughout his career, Chen-Ming Fan has worked at prestigious institutions such as the Massachusetts Institute of Technology and Harvard College. His research has contributed to advancements in understanding gene regulation and its implications in various biological processes.

Collaborations

Some of his notable coworkers include David Baltimore and Ranjan Sen, who have also made significant contributions to the field of molecular biology.

Conclusion

Chen-Ming Fan's innovative work in transcriptional regulation has paved the way for new discoveries in genetic research. His patents and collaborations reflect his commitment to advancing our understanding of gene expression and its applications in biotechnology.