Chen-Huan Chen

Title: Inventor Spotlight: Chen-Huan Chen from St. Louis, MO

Introduction

Chen-Huan Chen is a notable inventor based in St. Louis, MO, recognized for his contributions in the field of molecular biology. His work has significantly advanced the understanding of the hedgehog signaling pathway, particularly in relation to transcription factors and their phosphorylation states.

Latest Patents

Chen-Huan Chen holds a patent titled "Method for identifying a hedgehog-mediated phosphorylation state dependent transcription factor." This innovative invention provides crucial insights into transcription factors associated with the hedgehog signaling pathway, specifically how they are regulated by dephosphorylation by phosphatases. The patent also discusses hedgehog response elements (HRE) that interact with these dephosphorylated transcription factors. Furthermore, it outlines methods for identifying phosphatase inhibitors and potential treatments for tumors by modulating the phosphorylation of these transcription factors.

Career Highlights

With a focused career on the molecular mechanisms of cell signaling, Chen-Huan Chen has established himself as a key figure in his field. His work has not only contributed to scientific research but has also paved the way for potential therapeutic interventions that can impact cancer treatment.

Collaborations

Throughout his career, Chen has collaborated with esteemed colleagues such as Phillip A Beachy and Ming-Jer Tsai. These collaborations have fostered an environment of innovation and have significantly enriched his research contributions.

Conclusion

Chen-Huan Chen's innovative work and patent contributions illustrate the critical intersection of research and practical applications in the field of molecular biology. His insights into the hedgehog signaling pathway continue to inspire further research and development, showcasing the importance of inventors in advancing medical science.