This inventor holds 1 USPTO granted patent and 1 published patent application, plus 1 CIPO patent and 1 EPO patent. Top assignee: Quest Diagnostics Investments, Inc.. Active years: 2026.
Company Filing History:
Years Active: 2026
Title: Charles Rowland - Innovator in Non-Invasive Prenatal Screening
Introduction
Charles Rowland is an inventor based in San Juan Capistrano, California. He is currently associated with Quest Diagnostics Investments, Inc. Although he does not hold any granted patents, he has made significant contributions to the field of prenatal screening.
Latest Patent Applications
One of his notable patent applications is titled "Method for Non-Invasive Prenatal Screening for Aneuploidy." This application presents methods for non-invasive prenatal screening (NIPS) of fetal aneuploidies. The methods are based on analyzing cell-free fetal DNA (cff DNA) found in a pregnant woman's circulation through next-generation sequencing (NGS) technology. The application details how the relative abundance of different fetal genomic fragments present in the maternal sample can be aligned to specific chromosomal locations of the fetal genome. This information is indicative of whether a particular chromosome is overrepresented or underrepresented in a fetal genome compared to normal individuals, thus aiding in the detection of fetal aneuploidy. Additionally, the application discusses methods for increasing the positive predictive values (PPV) of NIPS by excluding false-positive detections.
Conclusion
Charles Rowland's work in non-invasive prenatal screening represents a significant advancement in medical technology, showcasing his innovative approach to improving prenatal care.