This inventor holds 2 USPTO granted patents. Top assignee: The United States of America, as Represented by the Secretary, Department of Health and Human Services. Active years: 2001-2006.
Company Filing History:
Years Active: 2001-2006
Title: Innovations by Charles Macri in Human Pathology and Physiology
Introduction
Charles Macri is an accomplished inventor based in Kensington, MD (US). He has made significant contributions to the field of human pathology and physiology, holding a total of 2 patents. His work focuses on the functional role of adrenomedullin (AM) and its implications in various diseases.
Latest Patents
Macri's latest patents include groundbreaking research on the functional role of adrenomedullin (AM) in human cancer cell lines. His inventions demonstrate that AM acts as a universal autocrine growth factor that drives neoplastic proliferation. The patents provide AM peptides and antibodies that are useful in therapeutic, pharmacologic, and physiologic compositions. Additionally, they outline methods for diagnosing, treating, and preventing diseases using these AM compositions. Notably, his research has shown that AM inhibits insulin secretion in a dose-dependent manner, and the monoclonal antibody MoAb-G6 can significantly increase insulin release.
Career Highlights
Charles Macri works for the United States of America, as represented by the Secretary, Department of Health and Human Services. His innovative research has contributed to a deeper understanding of the role of AM in pancreatic physiology and its potential therapeutic applications.
Collaborations
Macri has collaborated with notable coworkers, including Mae Jean Miller and Karen Gray, to advance his research and patent applications.
Conclusion
Charles Macri's contributions to the field of human pathology and physiology through his patents on adrenomedullin highlight the importance of innovation in medical research. His work continues to pave the way for new therapeutic approaches in treating diseases.