Company Filing History:
1 out of 6 
1 out of 2,202 
Years Active: 1998
Title: Innovations by Charles L. Chrespi: Advancements in Receptor-Ligand Detection
Introduction
Charles L. Chrespi is an accomplished inventor residing in Marblehead, Massachusetts, with a notable contribution to the field of biochemistry through his patent. With a focus on receptor-ligand complexes, Chrespi has made significant strides in enhancing the methods used for measuring promoter sequence activity in mammalian cells.
Latest Patents
Chrespi holds a patent titled "Method for detecting a receptor-ligand complex using a cytochrome P450." This innovative method introduces an improved way of measuring promoter activity by utilizing a reporter gene that features a DNA sequence encoding cytochrome P450 in combination with a polyadenylation signal sequence. The patented invention not only outlines the method itself but also encompasses compositions that include the cytochrome P450 reporter cassette, marking a substantial advancement in the field.
Career Highlights
Throughout his career, Chrespi has worked with various reputable organizations. He was notably associated with Gentest Corporation, where he contributed to the development of testing methodologies, and also worked with The United States of America As Represented by the Secretary of Health and Human Services, focusing on public health advancements.
Collaborations
Charles L. Chrespi has collaborated with esteemed colleagues such as Bruce W. Penman and Frank J. Gonzalez. Their combined efforts have likely propelled forward the research and application of innovative methods in the realm of cellular assays and biochemical applications.
Conclusion
In summary, Charles L. Chrespi's contributions through his patent demonstrate his commitment to advancing scientific knowledge in the field of biochemistry. His innovative methods for detecting receptor-ligand complexes using cytochrome P450 not only enhance our understanding but also pave the way for future research and applications in medicine and biotechnology. Chrespi's impressive career and collaborations further underscore the importance of teamwork and innovation in scientific exploration.