Company Filing History:
Years Active: 2001-2004
Title: The Innovative Contributions of Charles K Marschke
Introduction
Charles K Marschke is a notable inventor based in Kalamazoo, MI (US). He has made significant contributions to the field of biochemistry, particularly in the development of assays for protein kinases and phosphatases. With a total of 6 patents to his name, Marschke's work has advanced the understanding and application of biochemical processes.
Latest Patents
Marschke's latest patents include groundbreaking inventions such as fluorescence-based high throughput screening assays for protein kinases and phosphatases. This invention relates to novel fluorescence-based assays that can be utilized in high throughput screening. The methods involve a competitive immunoassay to determine the amount of substrate that is phosphorylated or dephosphorylated during kinase or phosphatase reactions.
Another significant patent focuses on methods for identifying compounds that bind to target species under isothermal denaturing conditions. This method includes incubating test mixtures under specific conditions to detect changes in the diffusion properties of target molecules using fluorescence correlation spectroscopy. This innovative approach allows for the identification of test compounds that interact with target species effectively.
Career Highlights
Charles K Marschke has had a distinguished career at Pharmacia & Upjohn Company, where he has contributed to various research initiatives. His work has not only led to the development of innovative assays but has also enhanced the capabilities of high throughput screening in biochemical research.
Collaborations
Marschke has collaborated with esteemed colleagues such as Dennis E Epps and Paul K Tomich. These collaborations have fostered a productive environment for innovation and have contributed to the advancement of their shared research goals.
Conclusion
In summary, Charles K Marschke's contributions to the field of biochemistry through his patents and collaborative efforts have significantly impacted the understanding of protein kinases and phosphatases. His innovative work continues to influence research and development in this vital area of science.