Company Filing History:
Years Active: 2002-2006
Title: Innovator Spotlight: Charles Issel
Introduction:
Charles Issel is a leading inventor based in Lexington, KY, known for his significant contributions to veterinary medicine, particularly in developing innovative vaccines. With a total of five patents to his name, he plays a crucial role in protecting animal health, specifically equines, against infectious diseases.
Latest Patents:
Issel's recent work includes groundbreaking patents in the field of equine infectious anemia (EIA) vaccines and diagnostics. The first notable invention is the EIA vaccine and diagnostic, which offers immunity to mammals, particularly equines, from the equine infectious anemia virus (EIAV). This vaccine not only protects against the infection but also allows differentiation between vaccinated and non-vaccinated mammals, even those exposed to the virus. Importantly, the vaccine's design ensures that it does not lead to clinical disease in mammals or spread among them.
Another significant patent is the EIAV p26 deletion vaccine and diagnostic, which provides immunity from infections caused by various lentiviruses. This innovation features a deletion in a gene that inhibits virus replication in vivo, offering protection against wild-type lentiviruses. Additionally, this vaccine incorporates a foreign gene that serves as a diagnostic tool for vaccinated mammals. It is a remarkable breakthrough that ensures equines can be vaccinated without testing positive on the Coggin's Test or similar evaluations.
Career Highlights:
Charles Issel has collaborated with various companies throughout his career, including Akzo Nobel N.V. His work has advanced the field of veterinary immunology and demonstrated his commitment to safeguarding animal welfare.
Collaborations:
In his innovative journey, Issel has worked alongside esteemed colleagues such as Ronald C. Montelaro and Bridget Puffer. Their collaborative efforts have contributed significantly to the development of effective vaccines and diagnostic techniques.
Conclusion:
Charles Issel stands out as a remarkable inventor whose work has made substantial impacts on equine health. His latest patents underscore his dedication to creating safe and effective vaccines, showcasing the importance of innovation in veterinary medicine. Through his continued efforts and collaborations, Issel remains a vital figure in the ongoing battle against infectious diseases in animals.