Location History:
- Sewell, NJ (US) (1997)
- Lawrenceville, GA (US) (2006 - 2016)
Company Filing History:
Years Active: 1997-2016
Title: **Inventor Spotlight: Charles E. Rupprecht**
Introduction
Charles E. Rupprecht is a prominent inventor based in Lawrenceville, GA, whose contributions to the field of virology and vaccine development have garnered significant attention. With a total of eight patents, Rupprecht has made remarkable advancements in combating rabies through innovative vaccine technology.
Latest Patents
Rupprecht's most recent patents focus on pan-lyssavirus vaccines against rabies. These vaccines incorporate recombinant rabies viruses that encode the rabies virus glycoprotein along with at least one heterologous glycoprotein from viruses like Mokola, Lagos bat, and West Caucasian bat viruses. Notably, certain embodiments of this invention feature two or three heterologous glycoproteins, which could serve as pan-vaccines to offer broad protection against rabies-causing viruses.
In addition, he has worked on patents that detail rabies virus compositions and methods. This research includes the full-length sequence of the Rabies Virus strain Evelyn-Rokitnicki-Abelseth (ERA) and introduces a reverse genetics system for producing recombinant ERA virus and its derivatives. The resulting compositions are immunogenic and hold promise for both pre- and post-exposure treatment of rabies.
Career Highlights
Throughout his career, Rupprecht has collaborated with noteworthy institutions, including the Government of the United States of America as represented by the Secretary of the Department of Health and Human Services and the University of Massachusetts. His work has had a profound impact on public health, particularly in the area of rabies prevention and treatment.
Collaborations
Collaboration has been a key element of Rupprecht's success. He has worked alongside esteemed colleagues such as Xianfu Wu and William D. Thomas, Jr., pooling their expertise to advance research and innovation in virology and vaccine development.
Conclusion
Charles E. Rupprecht stands out as a dedicated inventor contributing significantly to medical science through his innovative patents. His work not only furthers our understanding of rabies but also enhances our capacity to protect against this potentially fatal virus. Through collaborations with leading institutions and individuals, Rupprecht exemplifies the impact that committed inventors can have on public health and safety.