This inventor holds 1 USPTO granted patent. Top assignee: University of Virginia Patent Foundation. Active years: 1998.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
Years Active: 1998
Title: The Innovations of Charles E. Lyons, Jr.
Introduction
Charles E. Lyons, Jr. is a notable inventor based in Charlottesville, VA. He has made significant contributions to the field of molecular biology, particularly in the area of growth hormone research. His work has led to advancements in understanding the mechanisms of hormone receptor binding.
Latest Patents
Charles E. Lyons, Jr. holds a patent related to the molecular cloning of the ovine pituitary growth hormone releasing hormone (GHRH) receptor. This patent describes a unique binding assay utilizing iodinated GHRH probes for characterizing the receptor. Additionally, he has developed photoaffinity GHRH probes that facilitate photolabeling and characterization of the receptor. His work includes the construction of high-affinity biotinylated GHRH analogs and the solubilization of GHRH-R/GHRH complexes. The extraction of specifically bound GHRH using a mild detergent solution, followed by affinity chromatography, results in a substantially purified GHRH-R isolate. Furthermore, electrophoretic treatment of the GHRH-R isolate allows for sequencing of the receptor. His innovative approach also includes cloning a gene encoding polypeptides with GHRH-R activity using a bacterial host, with expression in a mammalian cell line.
Career Highlights
Charles E. Lyons, Jr. is associated with the University of Virginia Patent Foundation, where he continues to contribute to research and innovation. His work has been instrumental in advancing the understanding of growth hormone mechanisms and their applications in medicine.
Collaborations
He has collaborated with notable colleagues such as Michael Oliver Thorner and Reiko Horikawa, enhancing the impact of his research through teamwork and shared expertise.
Conclusion
Charles E. Lyons, Jr. exemplifies the spirit of innovation in the field of molecular biology, with his patent and research contributing to significant advancements in hormone receptor studies. His work continues to influence the scientific community and pave the way for future discoveries.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile