Company Filing History:
Years Active: 2002-2007
Title: The Innovative Journey of Charles D. Y. Sia
Introduction
Charles D. Y. Sia, an accomplished inventor based in Thornhill, CA, has made significant contributions to the field of medical science through his innovative patents. With a total of three patents to his name, Sia's work particularly focuses on advancing our understanding and treatment of HIV.
Latest Patents
One of Sia's latest patents involves expressing the gp140 fragment of a primary HIV-1 isolate. This patent outlines a vector designed to elicit an immune response in hosts by utilizing a gene encoding the gp140 protein of the primary isolate of HIV-1, known as BX08. The patent emphasizes the use of specific plasmids, including pCMV.gp140.BX08, pMP83, pMP84, and pMP88, and identifies murine and human MHC class 1-restricted binding motifs within BX08.
Another notable patent from Sia focuses on generating HIV-specific cytotoxic T-cell responses. This method involves initially administering a T-helper molecule to prime T-helper cells in the immune system of the host. Following this, a mixture of the T-helper molecule and a T-cell inducing HIV-derived molecule is administered to generate an HIV-specific T-cell response in the host.
Career Highlights
Throughout his career, Charles D. Y. Sia has worked with leading companies in the pharmaceutical industry, including Sanofi Pasteur Inc. and Aventis Pasteur Limited. His experience in these organizations has furthered his ability to innovate in the field of immunology and vaccine development.
Collaborations
In addition to his remarkable individual achievements, Sia has collaborated with notable colleagues including Roy Persson and Benjamin Rovinski. These partnerships have likely influenced and enhanced the development of his innovative concepts and patents, showcasing the importance of teamwork in advancing scientific research.
Conclusion
Charles D. Y. Sia stands out as a prominent inventor whose work is paving the way for breakthroughs in HIV research. His innovative patents reflect a commitment to improving health outcomes and addressing global health challenges through scientific inquiry and collaboration. With his impressive background and contributions, Sia continues to be a key figure in the pursuit of advanced medical solutions.