Company Filing History:
Years Active: 1998-2000
Title: Innovations of Charles C. Church: Advancements in Ultrasound Imaging
Introduction
Charles C. Church, an accomplished inventor based in Arlington, MA, has made significant contributions to the field of ultrasound imaging through his innovative research and patents. With a total of two patents to his name, Church's work primarily focuses on the enhancement of echogenicity and the development of microparticles for imaging applications.
Latest Patents
Church's latest patents include a groundbreaking method for enhancing the echogenicity and decreasing the attenuation of microparticles created from natural or synthetic polymers. His discovery reveals that microparticles with thicker walls demonstrate significantly improved echogenicity compared to those with thinner walls. By determining the optimal wall thickness, ranging from 100 to 660 nm, Church has paved the way for improved imaging capabilities. His microparticles, designed for targeted tissues, have varying diameters suitable for intravascular and oral administration, making them versatile for a range of medical applications.
In another notable patent, Church explores the incorporation of hydrophobic gases, particularly fluorinated gases, into microparticles formed from a combination of polymers and lipids. This innovation has demonstrated enhanced echogenicity compared to microparticles that do not contain lipids. Church emphasizes the use of synthetic biodegradable polymers and has outlined preferred polymers and lipids, which include various phospholipids that are essential for optimizing the formulations.
Career Highlights
Charles C. Church works at Acusphere, Inc., where his innovative research contributes to the advancement of medical imaging technologies. His dedication to enhancing ultrasound imaging capabilities has provided foundational advancements that have important implications in cardiology, blood perfusion applications, and organ imaging.
Collaborations
Throughout his career, Church has collaborated with notable colleagues such as Howard Bernstein and Julie A. Straub. Their collective efforts have been instrumental in pushing the boundaries of ultrasound imaging technology, fostering an environment of innovation and excellence at Acusphere, Inc.
Conclusion
In summary, Charles C. Church stands out as a significant inventor in the field of medical imaging, with advancements in microparticle technology that promise to revolutionize ultrasound imaging applications. His persistent drive for innovation and collaboration continues to enhance imaging techniques, benefitting both the medical community and patients alike.