Durham, NC, United States of America

Charles A Nichol


Average Co-Inventor Count = 3.7

ph-index = 6

Forward Citations = 103(Granted Patents)


Company Filing History:


Years Active: 1977-1990

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10 patents (USPTO):Explore Patents

Title: Charles A. Nichol: Innovator in Antiproliferative Treatments

Introduction

Charles A. Nichol is a prominent inventor based in Durham, NC (US), known for his significant contributions to the field of medicinal chemistry. With a total of 10 patents to his name, Nichol has made strides in developing innovative treatments that address critical health issues.

Latest Patents

Among his latest patents, Nichol has developed a treatment involving dialkoxy pyridopyrimidines, which exhibit potent antiproliferative activity while maintaining low inhibition of histamine N-methyltransferase. This class of compounds, specifically 2,4-diamino-6-(2,5-dialkoxybenzyl)-5-methylpyrido[2,3-d]pyrimidines, showcases promising therapeutic potential. Additionally, he has created biopterin analogs, which provide pterin compounds useful in both human and veterinary medicine. These compounds are characterized by formula (I), where R represents lower alkyl groups of 1-8 carbons, including all stereo isomers or pharmaceutically acceptable salts.

Career Highlights

Nichol has been associated with Burroughs Wellcome Co., where he has played a vital role in advancing pharmaceutical research and development. His work has significantly impacted the field, leading to innovative solutions for various medical challenges.

Collaborations

Throughout his career, Nichol has collaborated with notable colleagues, including David Stanley Duch and Carl W. Sigel. These partnerships have fostered a collaborative environment that enhances the innovation process.

Conclusion

Charles A. Nichol's contributions to medicinal chemistry and his innovative patents reflect his dedication to improving health outcomes. His work continues to inspire advancements in the field, showcasing the importance of innovation in medicine.

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