Company Filing History:
Years Active: 1999
Title: Charleen M Sullivan: Innovator in Genetic Research
Introduction
Charleen M Sullivan is a notable inventor based in Shrewsbury, MA, known for her significant contributions to genetic research, particularly in the field of neuromuscular diseases. With a focus on X-linked Charcot-Marie-Tooth disease, her work has implications for diagnostic methods and treatment avenues for affected individuals.
Latest Patents
Charleen holds a patent that addresses mutations relating to X-linked Charcot-Marie-Tooth disease. The patent details specific mutations in the connexin-32 gene, which are linked to this hereditary condition. It presents various methods for diagnosing X-linked Charcot-Marie-Tooth disease, including hybridization analysis techniques such as Southern or Northern analysis. The patent outlines direct mutation analysis through procedures like restriction digest and sequencing of the connexin-32 gene. Additionally, it describes the use of allele-specific oligonucleotides and the identification of mutant connexin-32 proteins. Notably, the patent covers mutant connexin-32 nucleic acid probes with mutations at 23 specific codons and the creation of probes with multiple mutations.
Career Highlights
Charleen is affiliated with Athena Diagnostics, Inc., where she has been instrumental in advancing genetic diagnostics. Her innovative approach and research have positioned her at the forefront of developments in genetic testing for neuromuscular disorders. The influence of her work is far-reaching, providing valuable insights into the diagnosis and potential treatment strategies for individuals affected by this debilitating disease.
Collaborations
Throughout her career, Charleen has collaborated with notable colleagues such as Uma Ananth and Michael Alan Boss. These collaborations have played a crucial role in enhancing the breadth and impact of her research, leading to significant advancements in the understanding and diagnosis of genetic conditions related to her work.
Conclusion
Charleen M Sullivan's contributions to genetic research have the potential to change lives by improving the diagnosis of X-linked Charcot-Marie-Tooth disease. Her innovative spirit, combined with her collaborations, exemplifies the vital role that inventors play in pushing the boundaries of scientific knowledge and medical practice.