This inventor holds 3 USPTO granted patents and 5 published patent applications, plus 2 CIPO patents and 2 EPO patents. Top assignee: Life Technologies Corporation. Active years: 2018-2023.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Location History:
- Clarence Center, NY (US) (2018)
- Germantown, MD (US) (2022 - 2023)
Company Filing History:
Years Active: 2018-2023
Title: Innovations by Chao Yan Liu
Introduction
Chao Yan Liu is an accomplished inventor based in Clarence Center, NY (US). He holds a total of 3 patents that contribute significantly to the field of biotechnology. His work primarily focuses on enhancing the production of adeno-associated virus (AAV) vectors and improving transient expression systems in mammalian cells.
Latest Patents
One of his latest patents is titled "Suspension system for adeno associated virus production." This technology relates to a production system designed to produce AAV vectors in a serum-free suspension platform and at high titers. The system utilizes reagents such as media, cells, transfection reagents, AAV enhancers, and lysis buffers, all aimed at maximizing AAV production from suspension cultures of mammalian cells, particularly HEK293 cells. With this innovative system, it is possible to deliver up to about 2×10 viral genomes per milliliter (vg/mL) of unconcentrated AAV vectors.
Another significant patent is "System and method for high-yield transient expression in mammalian cells." This invention provides high-yield mammalian transient expression systems that include cell culture media, particularly serum-free, non-animal derived, and chemically defined media. It allows for the introduction of macromolecules and compounds, such as nucleic acid molecules, into eukaryotic cells. The invention simplifies the process by eliminating the need to change the cell culture medium for different procedures, thus enhancing efficiency in cell culture and transfection.
Career Highlights
Chao Yan Liu is currently employed at Life Technologies Corporation, where he continues to innovate and develop new technologies in the field of biotechnology. His contributions have been instrumental in advancing methods for viral vector production and protein expression.
Collaborations
He collaborates with notable colleagues, including Sanjay Vasu and Jingqiu Li, who share his commitment to advancing biotechnological research and applications.
Conclusion
Chao Yan Liu's innovative work in the field of biotechnology, particularly in the production of AAV vectors and transient expression systems, showcases his significant contributions to the industry. His patents reflect a dedication to improving methodologies that enhance efficiency and effectiveness in biotechnological applications.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile