Chao Liu

Title: Innovations by Chao Liu in Carbohydrate and Peptide Sulfation

Introduction

Chao Liu is an accomplished inventor based in Newton, MA, with a focus on the sulfation of carbohydrates and peptides. He holds two patents that showcase his innovative approaches in this field. His work contributes significantly to the efficiency and effectiveness of synthesizing sulfated compounds.

Latest Patents

Chao Liu's latest patents include "Compositions and methods for sulfation of carbohydrates and peptides via electron-deficient aryl sulfate diesters." This patent describes a strategy to introduce electron-deficient aryl sulfate diesters to silylated hydroxyl groups of carbohydrates and amino acids. The method allows for selective hydrolysis and the removal of an electron-deficient aromatic group, leading to the efficient generation of sulfated carbohydrates, peptides, and other compounds. The incorporation of these diesters in the early stages of synthesis simplifies the purification process and improves overall yield and efficiency.

Career Highlights

Chao Liu is affiliated with The Trustees of Boston College, where he continues to advance research in carbohydrate and peptide chemistry. His innovative methods have the potential to streamline processes in various applications, enhancing the productivity of research in this area.

Collaborations

Chao Liu collaborates with notable colleagues, including Jia Niu and Cangjie Yang, who contribute to his research endeavors. Their combined expertise fosters a productive environment for innovation and discovery.

Conclusion

Chao Liu's contributions to the field of carbohydrate and peptide sulfation demonstrate his commitment to advancing scientific knowledge and improving synthesis methods. His patents reflect a significant step forward in the efficiency of producing sulfated compounds.