This inventor holds 1 USPTO granted patent. Top assignees: University of Colorado, University of Macau. Active years: 2021.
Company Filing History:
1 out of 1,447 
1 out of 77 
Years Active: 2021
Title: Changhao Chen: Innovator in Integrated Circuit Technology
Introduction
Changhao Chen is a prominent inventor based in Englewood, Colorado. He has made significant contributions to the field of integrated circuits, particularly in the area of neuroscience. His innovative work focuses on the intersection of electrophysiology and optogenetics, paving the way for advancements in neural engineering.
Latest Patents
Changhao Chen holds a patent for an integrated circuit designed for simultaneous electrophysiology recording and optogenetic neural control. This technology relates to a single monolithic integrated circuit (IC) that enables both optogenetic neural inhibition and extracellular electrophysiological recording in-vivo. The IC features a low input capacitance amplifier, specifically tailored for high-impedance electrodes, allowing for single neuron extracellular recording. Additionally, it integrates programmable high current drivers for optogenetic stimulation or inhibition on the same chip. The design process utilizes a noise model to optimize the signal-to-noise ratio. The performance of this IC was demonstrated on an anesthetized gerbil, where spontaneous action potentials were recorded and inhibited through laser illumination. This innovation opens new avenues for neuroscience research and has potential applications in treating human mental diseases.
Career Highlights
Throughout his career, Changhao Chen has worked at esteemed institutions such as the University of Macau and the University of Colorado. His research has significantly impacted the field of neural engineering, contributing to the development of technologies that enhance our understanding of brain functions.
Collaborations
Changhao has collaborated with notable colleagues, including Tim Lei and Achim Klug. These partnerships have fostered a collaborative environment that encourages innovation and the sharing of ideas in the field of neuroscience.
Conclusion
Changhao Chen's work in integrated circuit technology represents a significant advancement in neuroscience. His contributions have the potential to revolutionize the way we understand and treat mental health conditions.