Changging Wang

Title: Changging Wang: Innovator in Metabolic Modulation

Introduction

Changging Wang is a notable inventor based in Richmond, VA (US). He has made significant contributions to the field of biochemistry, particularly in the development of allosteric inhibitors of pyruvate kinase. His work has the potential to influence various metabolic processes, making it relevant for numerous medical applications.

Latest Patents

Changging Wang holds a patent for "Allosteric inhibitors of pyruvate kinase." This patent identifies chemical structures that allosterically modify pyruvate kinase, inhibiting its enzymatic activity. The compounds developed can be utilized as pharmaceuticals for treating a wide range of diseases and disorders. These include conditions where influencing metabolic processes is beneficial, such as in the glycolytic pathway, pathways using ATP as an energy source, and those involving 2,3-diphosphoglycerate related to oxygen delivery by modifying hemoglobin's oxygen affinity. His research also has implications for the treatment of tumors, cancer, and Alzheimer's disease (AD).

Career Highlights

Throughout his career, Changging Wang has demonstrated a commitment to advancing scientific knowledge and therapeutic options. His innovative approach to metabolic modulation has positioned him as a key figure in his field.

Collaborations

Changging Wang has collaborated with notable colleagues, including Donald J Abraham and Richmond E Danso-Danquah. These partnerships have likely contributed to the depth and impact of his research.

Conclusion

Changging Wang's work in developing allosteric inhibitors of pyruvate kinase showcases his innovative spirit and dedication to improving health outcomes. His contributions to biochemistry are paving the way for new therapeutic strategies in treating complex diseases.