Chang Won Kho

Title: Chang Won Kho: Innovator in Cardiovascular Disease Treatment

Introduction

Chang Won Kho is a prominent inventor based in New York, NY (US). He has made significant contributions to the field of cardiovascular medicine, particularly in the treatment of heart failure. His innovative approaches focus on the modulation of SERCA2a, a critical protein involved in cardiac function.

Latest Patents

Chang Won Kho holds a patent titled "Sumoylation of SERCA2a and cardiovascular disease." This patent outlines methods for treating cardiovascular disease, specifically heart failure, by administering a therapeutically effective amount of a modulator of SERCA2a post-translation modification, such as SUMOylation or acetylation. The patent also describes methods for diagnosing a propensity to develop heart failure by determining the presence of a SERCA2a mutant or the level of expression of SUMO1 in cardiomyocytes. Furthermore, it provides methods for screening therapeutics that modulate the post-translational modification of SERCA2a.

Career Highlights

Chang Won Kho is affiliated with the Icahn School of Medicine at Mount Sinai, where he conducts research and develops innovative treatments for cardiovascular diseases. His work has garnered attention for its potential to improve patient outcomes in heart failure.

Collaborations

Some of his notable coworkers include Roger Joseph Hajjar and Ah Young Lee, who collaborate with him on various research projects aimed at advancing cardiovascular medicine.

Conclusion

Chang Won Kho's contributions to the field of cardiovascular disease treatment highlight his innovative spirit and dedication to improving healthcare. His patent on SERCA2a modulation represents a significant advancement in the fight against heart failure.