Chang-Shan Hsu

Title: Chang-Shan Hsu: Innovator in Drug Delivery Systems

Introduction

Chang-Shan Hsu is a prominent inventor based in Taipei, Taiwan. He has made significant contributions to the field of pharmaceutical sciences, particularly in the development of innovative drug delivery systems. With a total of 2 patents, his work focuses on improving the oral administration of drugs that are typically unstable or poorly absorbed.

Latest Patents

One of his latest patents is titled "Oral administration of unstable or poorly-absorbed drugs." This patent discloses dosage forms and combinations that facilitate effective oral administration of drugs unsuitable for this route due to degradation by acid or digestive enzymes. The invention includes a self-microemulsifying drug delivery system (SMEDDS) that, when co-administered with an antacid, can prevent drug degradation and enhance absorption in the gastrointestinal tract. This method is particularly beneficial for administering insulin in a stable powder form that can be reconstituted before use.

Another significant patent is "Metronomic oral gemcitabine for cancer therapy." This patent describes compositions and methods for treating tumors in patients, including the use of gemcitabine in self-emulsifying orally administered dosage forms. The approach involves administering gemcitabine in a metronomic manner, allowing for repeated therapeutic doses over an extended period, which can effectively inhibit tumor growth.

Career Highlights

Chang-Shan Hsu is currently associated with Innopharmax, Inc., where he continues to innovate in drug delivery technologies. His work has the potential to transform how certain medications are administered, making them more effective and accessible to patients.

Collaborations

He collaborates with notable colleagues such as Wei-Hua Hao and Yu-Tsai Yang, contributing to a dynamic research environment that fosters innovation in pharmaceutical development.

Conclusion

Chang-Shan Hsu's contributions to drug delivery systems exemplify the importance of innovation in the pharmaceutical industry. His patents not only address critical challenges in drug administration but also pave the way for future advancements in patient care.