Chang Ohk Sung

Title: Chang Ohk Sung: Innovator in DNA Library Preparation

Introduction

Chang Ohk Sung is a notable inventor based in Yongin-si, South Korea. He has made significant contributions to the field of molecular biology, particularly in the preparation of DNA libraries from formalin-fixed, paraffin-embedded (FFPE) tissues. His innovative methods address critical challenges faced in clinical sample analysis.

Latest Patents

Chang Ohk Sung holds a patent for a method titled "Method for preparing DNA library derived from FFPE tissue using endonuclease." This invention is crucial as it provides a solution for preparing DNA libraries from FFPE tissues, which are commonly used in clinical settings. The method utilizes S1 nucleases, which specifically cleave single-stranded DNA, to facilitate the extraction of genomic DNA (gDNA) from FFPE tissues. By optimizing the elution process, this method reduces the need for the Covaris fragmentation process, thereby saving both time and costs associated with DNA library preparation.

Career Highlights

Chang Ohk Sung is associated with Genopeaks Co., Ltd., where he continues to advance research in DNA preparation techniques. His work has been instrumental in improving the efficiency of next-generation sequencing (NGS) analysis, particularly for older FFPE samples that often present challenges in DNA extraction.

Collaborations

He collaborates with talented colleagues, including Se-Jin Jang and Sung-Min Chun, who contribute to the innovative research environment at Genopeaks Co., Ltd. Their combined expertise enhances the development of cutting-edge solutions in molecular biology.

Conclusion

Chang Ohk Sung's contributions to the field of DNA library preparation represent a significant advancement in molecular biology. His innovative methods not only address existing challenges but also pave the way for more efficient clinical analyses.