Company Filing History:
2 out of 24 
1 out of 2,198 
1 out of 20 Years Active: 1995-2000
Title: Innovations in Complement Receptor Therapeutics by Chang-Jing Grace Yeh
Introduction
Chang-Jing Grace Yeh, an accomplished inventor based in Newton, MA, has made significant strides in the field of therapeutic innovations through his contributions to the realm of complement receptor technology. With a total of three patents to his name, his work primarily focuses on developing methods for making preparations of recombinant soluble Complement Receptor type 1 (sCR1) that have broad potential applications in treating various medical conditions.
Latest Patents
The latest patents awarded to Chang-Jing Grace Yeh detail groundbreaking methods related to sialylated glycoforms of soluble complement. These patents encompass crucial therapeutic methods for treating allograft or xenograft rejection, inflammatory diseases, inappropriate complement activation, and conditions associated with thrombosis or shock states. Notably, the methods emphasize the use of sCR1 glycoforms that exhibit specific properties such as being sialylated and having a defined pI or sialic acid to mannose molar ratio. These innovations indicate a focused approach toward enhancing therapeutic effectiveness and patient outcomes.
Career Highlights
Throughout his career, Chang-Jing has been affiliated with renowned companies like T Cell Sciences, Inc. and SmithKline Beecham Corporation. His expertise and insights have contributed significantly to advancements in therapeutic technologies, especially in the context of immune system modulation and potential clinical applications.
Collaborations
In his career journey, Chang-Jing has had the opportunity to collaborate with notable professionals such as Henry C. Marsh and Richard A. Smith. These collaborations have likely enriched his perspective and innovation approach, leading to impactful developments poised to benefit the medical field.
Conclusion
Chang-Jing Grace Yeh stands out as a remarkable inventor whose innovative work in the development of sialylated glycoforms of soluble complement receptors could transform therapeutic strategies in immunology and transplantation medicine. With his ongoing commitment to research and innovation, the potential for future breakthroughs remains promising.
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