Chang-Gong Liu

Title: Innovations in Cancer Diagnosis and Treatment by Chang-Gong Liu

Introduction

Chang-Gong Liu is a prominent inventor based in Pearland, TX (US), known for his significant contributions to the field of cancer research. He holds four patents that focus on the diagnosis and treatment of cancers through innovative methods involving microRNA.

Latest Patents

One of his latest patents addresses the diagnosis and treatment of cancers with microRNA located in or near cancer-associated chromosomal features. This invention highlights the strong association between microRNA genes and chromosomal features that play a crucial role in the etiology of various cancers. The genomic structure perturbations caused by these chromosomal features can influence the expression of nearby miR genes. By evaluating miR gene expression, it is possible to indicate the presence of cancer-causing chromosomal lesions in patients. Furthermore, restoring the level of miR gene expression to normal can potentially treat specific cancers. This microRNA expression profiling can also be utilized to diagnose cancer and predict adverse prognoses. The identification of mutations linked to genomic regions harboring miR genes in Chronic Lymphocytic Leukemia (CLL) patients offers a promising avenue for diagnosing CLL and possibly other cancers.

Career Highlights

Chang-Gong Liu is affiliated with Thomas Jefferson University, where he continues to advance research in cancer diagnostics and treatment. His work has garnered attention for its innovative approach to understanding the genetic underpinnings of cancer