Placentia, CA, United States of America

Chandra P Jain


Average Co-Inventor Count = 1.5

ph-index = 3

Forward Citations = 82(Granted Patents)


Company Filing History:


Years Active: 1982-2003

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3 patents (USPTO):Explore Patents

Title: Innovations by Chandra P Jain

Introduction

Chandra P Jain is an accomplished inventor based in Placentia, CA (US). He holds a total of 3 patents that showcase his contributions to the field of clinical applications and analytical chemistry. His work has significantly advanced the detection and measurement of important biological substances.

Latest Patents

One of his notable inventions is the lithium ion-selective electrode for clinical applications. This innovative electrode features a lithium ion-selective membrane that enhances the bonding of lithium while minimizing sodium interference through a charge balance approach. The electrode demonstrates a rapid kinetic response, high precision, and excellent reproducibility. It also retains its sensitivity after prolonged contact with biological samples. The sensor exhibits Nernst linearity with a slope of 55.4 mV for lithium ion concentrations ranging from 0.5 µmol/L to 10 mmol/L. The membrane composition includes approximately 2% by weight of 6,6-dibenzyl-1,4,8,11 tetraoxacyclotetradecane ionophore, along with potassium tetrakis(4-chlorophenyl)borate additive, a plasticizer, and a polymeric material.

Another significant patent involves a method and stable diazo reagent for detecting bilirubin. This improved reagent combination consists of a first solution containing an aryl amine and an acid, and a second solution with a nitrite compound. The reagent is characterized by the inclusion of a salt, which is distributed in a preselected manner within the solutions. The method allows for colorimetric determination of bilirubin in a sample by mixing aliquots of the two solutions to form a stable diazo reagent. This reagent is then used in conjunction with a total bilirubin accelerator buffer system to measure the color of azobilirubin formed from the coupling reaction with bilirubin present in the sample.

Career Highlights

Chandra P Jain has worked with reputable companies such as Beckman Instruments, Inc. and Beckman Coulter, Inc. His experience in these organizations has contributed to his expertise in developing innovative solutions in the field of clinical diagnostics.

Collaborations

Throughout his career, Jain has collaborated with notable individuals, including Xihai Mu and Frank R Shu. These partnerships have further enriched his work and expanded the impact of his inventions.

Conclusion

Chandra P Jain

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