Scotch Plains, NJ, United States of America

Chakravarthy Nachu Narasimhan

USPTO Granted Patents = 3 

 

 

Average Co-Inventor Count = 5.3

ph-index = 2

Forward Citations = 53(Granted Patents)


Company Filing History:


Years Active: 2015-2023

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3 patents (USPTO):Explore Patents

Title: Innovations by Chakravarthy Nachu Narasimhan

Introduction

Chakravarthy Nachu Narasimhan is a notable inventor based in Scotch Plains, NJ (US). He has made significant contributions to the field of biopharmaceuticals, particularly in the development of stable formulations for therapeutic antibodies. With a total of 3 patents, his work has the potential to impact cancer treatment and autoimmune disorders.

Latest Patents

One of his latest patents is focused on stable formulations of programmed death receptor 1 (PD-1) antibodies. This invention relates to stable formulations of antibodies against human programmed death receptor PD-1, or antigen binding fragments thereof. The formulations comprise between 5-200 mg/mL of anti-PD-1 antibody, and methods for treating various cancers are also provided. The formulations can be administered to a subject through intravenous or subcutaneous routes.

Another significant patent involves crystalline anti-human IL-23p19 antibodies. This patent provides crystalline forms of antibodies to human IL-23, including methods of producing such forms and their uses in treating inflammatory, autoimmune, and proliferative disorders. The anti-IL-23 antibody crystals maintain biological activity longer than corresponding solution formulations, offering increased stability.

Career Highlights

Chakravarthy Nachu Narasimhan is currently associated with Merck Sharp & Dohme Corporation, where he continues to innovate in the field of biopharmaceuticals. His work is characterized by a strong focus on improving the efficacy and stability of therapeutic antibodies.

Collaborations

He has collaborated with notable coworkers, including Manoj K Sharma and Ramesh Kashi, contributing to advancements in their respective fields.

Conclusion

Chakravarthy Nachu Narasimhan's contributions to the development of stable antibody formulations highlight his role as an influential inventor in the biopharmaceutical industry. His innovative work continues to pave the way for new treatment options in cancer and autoimmune diseases.

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